Science News
Discover the news and inspiring materials from the world of biotechnology.
Effectiveness of 2023-24 season COVID vaccines: First estimates are in
First studies estimating the effectiveness of updated COVID-19 vaccines have been published. Effectiveness against hospitalization was calculated at 70.7%-76.1% and against symptomatic SARS-CoV-2 infection at 54%.
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Monoclonal antibody targeting CD3 receptor preserves insulin secretion in early type 1 diabetes
Teplizumab, an anti-CD3 monoclonal antibody, was found to preserve the function of pancreatic β cells in newly diagnosed type 1 diabetes mellitus. Earlier, the drug has received FDA approval in the prevention of type 1 diabetes in high-risk individuals.
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Beacon Select System™ opens new technological chapter in Mabion
We are thrilled to announce that Mabion S.A. has recently acquired the cutting-edge Beacon Select™ System for cell line development (CLD).
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EMA and FDA investigating cancer signal for CAR-T therapies
EMA and FDA have started a safety review of CAR-T therapies following the notification of 23 cases of T-cell malignancies. The investigation involves all registered CAR-T products, which are used for treating relapsed and treatment-resistant hematologic malignancies.
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Antisense therapy fails to delay the progression of Huntignton’s disease
A trial of investigational antisense therapy for Huntington’s disease, tominersen, has been halted early for lack of efficacy and possibly harm with more frequent dosing. However, the quest for effective therapy of Huntington’s disease is still ongoing and the developer of tominersen decided to continue research, this time enrolling younger patients with early disease.
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Bispecific antibodies: success story continues
A great number of clinical studies confirmed high efficacy and safety of bispecific antibodies in the treatment of various cancers. Breaking results from another three, evaluating amivantamab, blinatumomab and tarlatamab, continue their success story.
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Moderna succeeds in the pivotal trial of RSV vaccine
An mRNA-based vaccine against respiratory syncytial virus (RSV) succeeded in a Phase III trial conducted in elderly subjects. Vaccine efficacy was 83.7% against RSV-related lower respiratory tract disease with at least two symptoms. It is hoped that the use of RSV vaccines along with influenza and COVID-19 immunization campaigns will further mitigate the morbidity and mortality of elderly people during the winter seasons.
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A new affordable HPV vaccine will help fight cervical cancer
Novel HPV vaccine manufactured by Serum Institute of India (Cervavac®) elicits comparable immune responses and is as safe as the original HPV vaccine. Availability of a cheaper version of HPV vaccine can foster the global efforts to reduce the incidence of cervical cancer.
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